Use of rhBMP-2 to reconstruct a severely atrophic mandible: a modified approach
Identifieur interne : 003E49 ( Main/Exploration ); précédent : 003E48; suivant : 003E50Use of rhBMP-2 to reconstruct a severely atrophic mandible: a modified approach
Auteurs : N. M. A. Lopes [Brésil] ; A. Vajgel [Brésil] ; D. M. De Oliveira [Brésil] ; T. De Santana Santos [Brésil] ; T. Wassall [Brésil]Source :
- International journal of oral and maxillofacial surgery [ 0901-5027 ] ; 2012.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Chirurgie.
English descriptors
- KwdEn :
Abstract
This study reports the case of a patient with a severely resorbed mandible who was treated without a bone graft, using short implants, internal rigid fixation, rhBMP-2 and β-tricalcium phosphate. A 76-year-old woman, with a severely resorbed mandible (less than 3 mm), reported a history of nearly 25 years of complete edentulism and consecutive treatment failures, with total bilateral exposed inferior alveolar nerves and complete bone resorption of the inferior border in some areas. The treatment of choice was the placement of a 2.0 mm thick unilock bone plate (MatrixMandible, Synthes Maxillofacial, Paoli, PA, USA), to reinforce the mandible. Eight short implants with a regular platform (Nobel Biocare, Goteborg, Sweden) were placed: three on the external oblique line on both sides and two on the symphysis. In order to augment mandible height and coat the exposed thread of the anterior implants, rhBMP-2 (Infuse Bone, Meditronic Sofamor Danek, Memphis, TN, USA) and β-tricalcium phosphate (Cerasorb; Curasan, Kleinostheim, Germany) were used. Four 1.3 mm L miniplates were placed to support the graft. 14 months after surgery, the patient was satisfied and had excellent function without complications.
Affiliations:
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M. A." last="Lopes">N. M. A. Lopes</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Faculdade São Leopoldo Mandic</s1><s2>Campinas-SP</s2><s3>BRA</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Brésil</country><placeName><region type="state">État de São Paulo</region></placeName></affiliation></author><author><name sortKey="Vajgel, A" sort="Vajgel, A" uniqKey="Vajgel A" first="A." last="Vajgel">A. Vajgel</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>University of Pernambuco Recife</s1><s2>PE</s2><s3>BRA</s3><sZ>2 aut.</sZ></inist:fA14><country>Brésil</country><placeName><region type="state">Pernambuco</region></placeName></affiliation></author><author><name sortKey="De Oliveira, D M" sort="De Oliveira, D M" uniqKey="De Oliveira D" first="D. M." last="De Oliveira">D. M. De Oliveira</name><affiliation wicri:level="2"><inist:fA14 i1="03"><s1>Maurício de Nassau School (FMN)</s1><s2>Recife, PE</s2><s3>BRA</s3><sZ>3 aut.</sZ></inist:fA14><country>Brésil</country><placeName><region type="state">Pernambuco</region></placeName></affiliation></author><author><name sortKey="De Santana Santos, T" sort="De Santana Santos, T" uniqKey="De Santana Santos T" first="T." last="De Santana Santos">T. De Santana Santos</name><affiliation wicri:level="4"><inist:fA14 i1="04"><s1>University of São Paulo</s1><s2>Ribeirão Preto, SP</s2><s3>BRA</s3><sZ>4 aut.</sZ></inist:fA14><country>Brésil</country><placeName><region type="state">État de São Paulo</region><settlement type="city">São Paulo</settlement></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Wassall, T" sort="Wassall, T" uniqKey="Wassall T" first="T." last="Wassall">T. Wassall</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Faculdade São Leopoldo Mandic</s1><s2>Campinas-SP</s2><s3>BRA</s3><sZ>1 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Brésil</country><placeName><region type="state">État de São Paulo</region></placeName></affiliation></author></analytic><series><title level="j" type="main">International journal of oral and maxillofacial surgery</title><title level="j" type="abbreviated">Int. j. oral maxillofac. surg.</title><idno type="ISSN">0901-5027</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">International journal of oral and maxillofacial surgery</title><title level="j" type="abbreviated">Int. j. oral maxillofac. surg.</title><idno type="ISSN">0901-5027</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Mandible</term><term>Stomatology</term><term>Surgery</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Chirurgie</term><term>Mandibule</term><term>Stomatologie</term><term>Traitement</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study reports the case of a patient with a severely resorbed mandible who was treated without a bone graft, using short implants, internal rigid fixation, rhBMP-2 and β-tricalcium phosphate. A 76-year-old woman, with a severely resorbed mandible (less than 3 mm), reported a history of nearly 25 years of complete edentulism and consecutive treatment failures, with total bilateral exposed inferior alveolar nerves and complete bone resorption of the inferior border in some areas. The treatment of choice was the placement of a 2.0 mm thick unilock bone plate (MatrixMandible, Synthes Maxillofacial, Paoli, PA, USA), to reinforce the mandible. Eight short implants with a regular platform (Nobel Biocare, Goteborg, Sweden) were placed: three on the external oblique line on both sides and two on the symphysis. In order to augment mandible height and coat the exposed thread of the anterior implants, rhBMP-2 (Infuse Bone, Meditronic Sofamor Danek, Memphis, TN, USA) and β-tricalcium phosphate (Cerasorb; Curasan, Kleinostheim, Germany) were used. Four 1.3 mm L miniplates were placed to support the graft. 14 months after surgery, the patient was satisfied and had excellent function without complications.</div></front></TEI><affiliations><list><country><li>Brésil</li></country><region><li>Pernambuco</li><li>État de São Paulo</li></region><settlement><li>São Paulo</li></settlement><orgName><li>Université de São Paulo</li></orgName></list><tree><country name="Brésil"><region name="État de São Paulo"><name sortKey="Lopes, N M A" sort="Lopes, N M A" uniqKey="Lopes N" first="N. M. A." last="Lopes">N. M. A. Lopes</name></region><name sortKey="De Oliveira, D M" sort="De Oliveira, D M" uniqKey="De Oliveira D" first="D. M." last="De Oliveira">D. M. De Oliveira</name><name sortKey="De Santana Santos, T" sort="De Santana Santos, T" uniqKey="De Santana Santos T" first="T." last="De Santana Santos">T. De Santana Santos</name><name sortKey="Vajgel, A" sort="Vajgel, A" uniqKey="Vajgel A" first="A." last="Vajgel">A. Vajgel</name><name sortKey="Wassall, T" sort="Wassall, T" uniqKey="Wassall T" first="T." last="Wassall">T. Wassall</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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